Zinc Stabilizes Key Cancer Protein, Offers New Treatment Hope
A groundbreaking study by the Wilmot Cancer Institute has discovered that zinc can stabilize a protein, p53, which is crucial in preventing most cancers. This finding, led by Professor Darren Carpizo, M.D., Ph.D., of the University of Rochester Medical Center, could significantly impact cancer treatment.
p53, the most commonly mutated cancer gene, is a key factor in nearly every type of cancer. The new research shows that raising zinc levels in cells can stabilize a broad group of p53 mutations, potentially benefiting over 120,000 cancer patients annually in the U.S.
Zinc's role in cancer prevention has been further explored with the development of zinc-based drugs. These drugs include a 'chaperone' component that delivers zinc directly to cancer cells, bypassing the issue of ineffective absorption through common supplements like Zicam. Researchers are optimistic about the potential of these drugs to treat a wide range of cancers.
The discovery that zinc can stabilize p53 opens up new avenues for cancer treatment. While further research is needed, these findings suggest that zinc-based drugs could significantly improve cancer outcomes. Dr. Carpizo, chief of Surgical Oncology at Wilmot Cancer Institute, is at the forefront of this exciting development.
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