Zepatier Dosage Information: Forms available, potencies, administration methods, and additional details
In a significant breakthrough for those suffering from chronic hepatitis C, the drug Zepatier (elbasvir/grazoprevir) has been approved for treatment. This direct-acting antiviral, which is not available in a generic version, is similar in form and frequency of administration to Harvoni for certain types of hepatitis C.
Zepatier is prescribed for adults and children who are 12 years old or older, or who weigh a certain amount. The recommended dosage for both adults and children is one tablet taken once per day. It's important to note that the safety and efficacy of Zepatier have not been established in children under 12 years of age and weighing less than 30 kg, so its use in this pediatric group is not recommended.
For adults with genotype 1b infection, the typical duration of treatment is 12 weeks. For genotype 1a patients who have failed prior PEG-IFN/RBV treatment and have no baseline NS5A resistance-associated substitutions (RAS), the duration is also 12 weeks. Other genotype and treatment-experience scenarios might require adjustments, but the main official dosage remains a once-daily tablet for 12 weeks in these populations.
No specific dosage modification for older adults or children above 12 is indicated, but treatment decisions should consider liver function and the presence of cirrhosis.
To ensure effective treatment, Zepatier should ideally be taken around the same time of day. If you miss a dose, take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose. You likely won't feel Zepatier working in your body, but rest assured that it starts to work after the first dose.
Remembering doses can be a challenge, and that's where technology can help. Downloading a reminder app on your phone can be a useful tool. Additionally, some pharmacies offer labels with large print, braille, or a code for smartphone scanning for accessibility.
For more information about Zepatier, side effects, or hepatitis C, refer to the provided articles. It's crucial to always follow the dosage prescribed by your doctor. If you have trouble opening medication bottles, ask your pharmacist about easy-open containers or tools that can help. Zepatier can be taken with or without food.
In summary, Zepatier 50 mg elbasvir/100 mg grazoprevir once daily for 12 weeks is the main recommended regimen in adults with chronic hepatitis C caused by genotypes 1 or 4, with pediatric and other age-group data limited.
References: [1] [Source 1] [5] [Source 5]
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