News Article: Innovative Methods for Pyriofenone Analysis in Soil
Soil Analysis of Pyriofenone using ECM - Identification Number 49256126
In a groundbreaking study, ISK Biosciences Corporation has developed an advanced method for detecting and quantifying Pyriofenone residues in soil using liquid chromatography-tandem mass spectrometry (LC/MS/MS). The study, identified by Matrix Resource Identification (MRID) 49256126, employs three distinct methods: Extractable Chemical Method (ECM), Independent Laboratory Validation (ILV), and Data Evaluation Report Method (DER).
Extractable Chemical Method (ECM)
The ECM involves the extraction and isolation of Pyriofenone residues from soil samples. This method targets the fraction of the chemical that is available in the soil matrix after sample collection. The process includes sample preparation, solvent extraction, cleanup, and the production of a solution containing the free (extractable) Pyriofenone residues.
Independent Laboratory Validation (ILV)
To verify the reliability and reproducibility of the analytical method, an independent laboratory replicates key parts of the analysis, assessing parameters such as accuracy, precision, linearity, limit of detection (LOD), limit of quantification (LOQ), specificity, and robustness. The validation includes fortified soil samples with known concentrations of Pyriofenone, spanning the expected residue range.
Data Evaluation Report Method (DER)
The DER provides a comprehensive methodological approach, summarizing and submitting details on method performance, data analysis, and interpretation for regulatory review. The DER includes LC/MS/MS conditions, chromatographic conditions, mass spectrometric detection, calibration, quality control, and data validation.
The combined use of ECM, ILV, and DER steps ensures the analytical method complies with regulatory requirements for pesticide residue analysis. The Limit of Quantitation (LOQ) for the analysis is 1.0 μg/kg.
The Environmental Protection Agency (EPA) does not validate the methods but acknowledges they may be useful to state, tribal, and local authorities. The news article was published on July 6, 2007. For more precise details such as solvent types, extraction times, chromatography gradients, or mass spec parameters from the ISK Biosciences study MRID 49256126, those specifics reside within the full study report or the publicly available EPA documents associated with MRID references.
The file sizes for the ECM, ILV, and DER analyses of Pyriofenone in Soil are 218.69 KB, 110.8 KB, and 563.81 KB, respectively. The Matrix Resource Identifications (MRIDs) for the ECM and ILV analyses are 49256126 and 49256127, respectively.
It's essential to note that the methods discussed in the article may not have undergone independent validation by the EPA. The analysis was conducted by ISK Biosciences Corporation, and the methods are intended for use by state, tribal, and local authorities.
In the innovative study by ISK Biosciences Corporation, the combined methods of Extractable Chemical Method (ECM), Independent Laboratory Validation (ILV), and Data Evaluation Report Method (DER) are applied to analyze Pyriofenone residues in soil, which contribute significantly to health-and-wellness, medical-conditions, and environmental-science sectors. These methods aim to ensure compliance with regulatory requirements for pesticide residue analysis in soil samples, providing reliable and reproducible results.
