Pyogenic Liver Abscess Cases Rising: Diabetes Patients at Higher Risk

Diabetes patients face a 3.6x higher risk. Early diagnosis and treatment vital to prevent life-threatening complications.

, and Administrator

2025 October 8 . 11:10 AM

1 min read

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Pyogenic Liver Abscess Cases Rising: Diabetes Patients at Higher Risk

A pyogenic liver abscess (PLA), a serious bacterial infection causing a pus-filled pocket in the liver, has been on the rise, particularly among diabetes mellitus patients. Prompt diagnosis and treatment are crucial, as sepsis and organ infections can occur, making it potentially fatal.

PLA symptoms include chills, vomiting, fever, right upper abdominal pain, sudden weight loss, dark urine, clay-colored stool, and diarrhea. Diagnosis involves blood cultures, abdominal ultrasound, CT scan, blood tests, and MRI of the abdomen. People with diabetes mellitus are at 3.6 times higher risk due to increased infection susceptibility.

Treatment requires comprehensive antibiotic therapy. Intravenous antibiotics like Ceftriaxon, Cefotaxim, or Ampicillin/Sulbactam are commonly used. Metronidazole may also be added to cover Anaerobier. Once the infection is under control, oral antibiotics such as Ciprofloxacin with Metronidazole or Amoxicillin-Clavulansäure can be prescribed. The choice of antibiotics should be based on lab results and clinical response, with treatment duration varying depending on infection severity and individual healing progress.

PLA, a life-threatening condition if left untreated, can be caused by biliary disease in up to 50% of cases, with other causes including ruptured appendix, pancreatic cancer, and colon cancer. Prompt diagnosis and surgical treatment, along with appropriate antibiotic therapy, are vital for a positive outlook. Early intervention can prevent complications like sepsis and organ infections, ensuring better patient recovery.