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New Study: High Blood Sugar Harms Crucial Nerve Network

High blood sugar can damage a vital nerve network. This discovery could change how we treat sacral plexus disorders and support cancer patients.

This is a collage. In this we can see a person's leg with tattoo.
This is a collage. In this we can see a person's leg with tattoo.

New Study: High Blood Sugar Harms Crucial Nerve Network

New research from the University of Heidelberg, led by Dr. Maria Schneider in 2024, has shed light on the impact of high blood sugar levels on the sacral plexus. This crucial nerve network supplies motor and sensory nerves to the pelvis, buttocks, thighs, and lower limbs. The findings could revolutionise treatment for those affected by sacral plexus disorders.

The sacral plexus, one of five major plexuses in the body, rests on the piriformis muscle in the hip area. It provides essential nerve connections to the lower body, enabling movement and sensation. However, high blood sugar levels can interfere with its proper functioning, leading to weakness, loss of sensation, or pain in the lower limbs and buttocks.

Dr. Schneider's research has shown that managing blood sugar levels can help mitigate these symptoms and potentially prevent further damage. This is particularly relevant for cancer patients undergoing radiation therapy, who are at risk of damaging the sacral plexus even if the radiation is targeted elsewhere in the body. Electromyography and magnetic resonance imaging (MRI) are commonly used to confirm a diagnosis involving the sacral plexus.

Dr. Schneider's groundbreaking work highlights the importance of blood sugar management in maintaining the health of the sacral plexus. Further research is needed to fully understand the extent of this relationship and develop targeted treatments. Meanwhile, cancer patients and those with diabetes should be aware of the potential impact of high blood sugar on this vital nerve network.

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